Do you ever blend a bunch of strains together? Not sure if it is the entourage effect or something else, but I get wrecked hard.
I have a little jar right now that has a mixture of Cinderella 99, White Widow, Blueberry Muffin, Blueberry Hashplant, Korengal Kush and StarTropic CBD. I can vape any combination of those separately all day and get high, but hitting a combo bowl is something different altogether.
I personally believe the entourage effect to be valid myself; There's some strains that will have you wondering what is in your pocket for 20 minutes (like Chem D and Motor Breath) but a combo ? You'll forget you have pockets if you hit it enough LOL.
I mean it stands to reason that, outside of pulling plants early, at their peak, or "late" is really the only change you're going to make to THC in that plant (Pull it when it's not that cloudy, more Sativa effect, pull ti mainly cloudy, most THC content, pull it Amber / Purple, Indica effects) so the only real difference in two strains, would be the Terpenes, and I'm quite confident that this matters. It's no secret around here that years ago I didn't even really smoke that much, and didn't care about strain names, and then, I smoked Blue Cheese and instantly cared. I've grown a lot of different strains now and can pretty assuredly think that Terpene Profile changes everything.
I've had Chem D pulled early, I've had Chem D pulled for higher THC (90% cloudy resin) and I'v had Chem D I left until it was nice and Amber looking, and to be honest, there really wasn't THAT much difference outside of the late pull helping get you tired. You smoke 4 of those regardless of pull and you're still walking around outside forgetting what you went out there for LOL.
Blue Cheese I cut multiple times; One for day time, one for night time, and....The hand full I leave on my tray until it's dry enough to grind LOL.